A Natural Killer Cell that is uniquely attracted to Borrelia
The human immune system consists of several different types of white blood cells with one category being called Lymphocytes. Lymphocytes consists of 3 subcategories of white blood cells known as B-Cells, T-Cells, and Natural Killer Cells. B-Cells are responsible for antibody production, while T-Cells and Natural Killer Cells are responsible for killing foreign invaders. CD57 is a natural killer cell. "CD" stands for "Cluster Designation" which is simply a molecule on the cell that gives the CD57 cell its identity. The "57" in CD57 is just an implication of the numerical order it was discovered in.
It is generally believed that the lower the amount of CD57 natural killer cells in the body, the more chronic or progressive Lyme disease is, and the higher the amount, the closer a person is to remission. There have been instances where high amounts of CD57 natural killers cells have been found in those with chronic Lyme disease, and low amounts of CD57 natural killer cells have been found in those who were believed to be in remission. While the CD57 test is not 100% accurate in terms of diagnosing chronic Lyme disease, it is an incredibly useful test in doing so when it is compared with other diagnostic Lyme tests such as a western blot test or the c3a and c3a complement protein test, as well as a person's symptoms.
The progression of Lyme Disease is discretionarily determined by the graph below.
- A CD57 natural killer cell level of about 200 is believed to be the area in which it is safe to discontinue use of a protocol without the risk of encountering a relapse.
- Even if your symptoms disappear, you should still continue with treatment until your CD57 reaches about 200 to avoid a relapse.
- 200 is also the level where CD57 natural killer cells should naturally reside.
- High CD57 levels with symptoms could be an indication that one is actually dealing with a co-infection as opposed to Lyme itself.
- SAVELY, GINGER, RN, and FNP-C. "Understanding The CD 57 Test « HOPE TO HEAL." HOPE TO HEAL. N.p., n.d. Web. 14 Feb. 2012. <http://heallyme.wordpress.com/2009/01/28/understanding-the-cd-57-test/>
- LymeMD: CD57." LymeMD. N.p., n.d. Web. 15 Feb. 2012. <http://lymemd.blogspot.com/2009/01/cd57.html>
- Image from Wikipedia: http://upload.wikimedia.org/wikipedia/commons/8/89/SEM_Lymphocyte.jpg , Author: Dr. Triche National Cancer Institute , License: Creative Commons Attribution-Share Alike 3.0
Disclaimer: The information on this page is not intended to diagnosis, prevent, treat or cure any disease. Always consult with your doctor before starting or ending a treatment protocol. The CD57 Test is used by some physicians to discretionarily confirm suspicions of Lyme disease and remission. The test is not an official or accurate means of diagnosing Lyme disease or to determine the state of remission.